BAG3 Antikörper (AA 380-575)
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- Target Alle BAG3 Antikörper anzeigen
- BAG3 (BCL2-Associated Athanogene 3 (BAG3))
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Bindungsspezifität
- AA 380-575
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BAG3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
- Verwendungszweck
- BAG3 Rabbit pAb
- Sequenz
- PSAVPSSPKS VATEERAAPS TAPAEATPPK PGEAEAPPKH PGVLKVEAIL EKVQGLEQAV DNFEGKKTDK KYLMIEEYLT KELLALDSVD PEGRADVRQA RRDGVRKVQT ILEKLEQKAI DVPGQVQVYE LQPSNLEADQ PLQAIMEMGA VAADKGKKNA GNAEDPHTET QQPEATAAAT SNPSSMTDTP GNPAAP
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 380-575 of human BAG3 (NP_004272.2).
- Isotyp
- IgG
- Top Product
- Discover our top product BAG3 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100,IP,1:50 - 1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- BAG3 (BCL2-Associated Athanogene 3 (BAG3))
- Andere Bezeichnung
- BAG3 (BAG3 Produkte)
- Hintergrund
- BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.,BAG3,BAG-3,BIS,CAIR-1,MFM6,Cancer,Invasion and Metastasis,Cell Biology & Developmental Biology,Apoptosis,Bcl 2 family,Endocrine & Metabolism,BAG3
- Molekulargewicht
- 61kDa
- Gen-ID
- 9531
- UniProt
- O95817
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