ABCB7 Antikörper (AA 503-753)

Produktnummer ABIN7265735

Der Kaninchen Polyklonal Anti-ABCB7-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet, ABCB7 in Proben von Human zu detektieren.

Kurzübersicht für ABCB7 Antikörper (AA 503-753) (ABIN7265735)

Target: ABCB7 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCB7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-ABCB7 Antikörper

Bindungsspezifität: AA 503-753

Verwendungszweck: ABCB7 Rabbit pAb

Sequenz: AIVGGSGSGK STIVRLLFRF YEPQKGSIYL AGQNIQDVSL ESLRRAVGVV PQDAVLFHNT IYYNLLYGNI SASPEEVYAV AKLAGLHDAI LRMPHGYDTQ VGERGLKLSG GEKQRVAIAR AILKDPPVIL YDEATSSLDS ITEETILGAM KDVVKHRTSI FIAHRLSTVV DADEIIVLDQ GKVAERGTHH GLLANPHSIY SEMWHTQSSR VQNHDNPKWE AKKENISKEE ERKKLQEEIV NSVKGCGNCS C

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 503-753 of human ABCB7 (NP_004290.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ABCB7

Target: ABCB7 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7))

Andere Bezeichnung: ABCB7

Hintergrund: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,ABCB7,ABC7,ASAT,Atm1p,EST140535,Signal Transduction,Endocrine & Metabolism,Stem Cells,Hematopoietic Progenitors,ABCB7

Molekulargewicht: 78kDa/82kDa

Gen-ID: 22

UniProt: O75027

Pathways: Transition Metal Ion Homeostasis