ADAM11 Antikörper (AA 290-430)

Produktnummer ABIN7265433

Der Kaninchen Polyklonal anti-ADAM11 Antikörper (ABIN7265433) detektiert spezifisch ADAM11 in WB und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ADAM11 Antikörper (AA 290-430) (ABIN7265433)

Target: ADAM11 (ADAM Metallopeptidase Domain 11 (ADAM11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAM11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-ADAM11 Antikörper

Bindungsspezifität: AA 290-430

Verwendungszweck: ADAM11 Rabbit pAb

Sequenz: METWADGDKI QVQDDLLETL ARLMVYRREG LPEPSDATHL FSGRTFQSTS SGAAYVGGIC SLSHGGGVNE YGNMGAMAVT LAQTLGQNLG MMWNKHRSSA GDCKCPDIWL GCIMEDTGFY LPRKFSRCSI DEYNQFLQEG G

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 290-430 of human ADAM11 (NP_002381.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ADAM11

Target: ADAM11 (ADAM Metallopeptidase Domain 11 (ADAM11))

Andere Bezeichnung: ADAM11

Hintergrund: This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,ADAM11,MDC,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,ADAM Protein Family,Ubiquitin,ADAM11

Molekulargewicht: 57kDa/83kDa

Gen-ID: 4185

UniProt: O75078