AHSA1 Antikörper
Kurzübersicht für AHSA1 Antikörper (ABIN7265410)
Target
Alle AHSA1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- AHA1 Rabbit mAb
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Monoclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthesized peptide derived from human AHA1
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- AHSA1 (Activator of HSP90 ATPase Activity 1 (AHSA1))
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Andere Bezeichnung
- AHSA1
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Hintergrund
- AHA-1 stimulates the inherent ATPase activity of yeast and human HSP 90 and interacts with the cytoplasmic tail of vesticular stomatitis virus glycoprotein. AHA-1 regulates HSP 90 by influencing the conformational state of the ""ATP lid"" and consequent N-terminal dimerization. It is crucial for cell viability under non-optimal growth conditions when HSP 90 levels are limiting. AHA-1 is a cytosolic protein and may transiently interact with the endoplasmic reticulum. It can have an affect on one step in the endoplasmic to Golgi trafficking. AHA-1 is expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, in liver and placenta. It is induced by heat shock and treatment with the HSP 90 inhibitor 17-demeth-oxygeldanamycin.,AHA1, C14orf3, hAha1, p38,Signal Transduction,AHSA1
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Molekulargewicht
- 43kDa
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Gen-ID
- 10598
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UniProt
- O95433
Target
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