OAS1 Antikörper (AA 1-100)
Kurzübersicht für OAS1 Antikörper (AA 1-100) (ABIN7265323)
Target
Alle OAS1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-100
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Verwendungszweck
- OAS1 Rabbit pAb
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Sequenz
- MMDLRNTPAK SLDKFIEDYL LPDTCFRMQI NHAIDIICGF LKERCFRGSS YPVCVSKVVK GGSSGKGTTL RGRSDADLVV FLSPLTTFQD QLNRRGEFIQ
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Kreuzreaktivität
- Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 1-100 of human OAS1 (NP_002525.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
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Andere Bezeichnung
- OAS1
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Hintergrund
- This gene is induced by interferons and encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12.,OAS1,E18/E16,IFI-4,OIAS,OIASI,Epigenetics & Nuclear Signaling,OAS1
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Molekulargewicht
- 41kDa/43kDa/46kDa/47kDa
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Gen-ID
- 4938
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UniProt
- P00973
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Pathways
- Hepatitis C
Target
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