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Nlgn4l Antikörper (C-Term)

Dieses Anti-Nlgn4l-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Nlgn4l in IHC, WB und IF/ICC. Geeignet für Maus.
Produktnummer ABIN7233051

Kurzübersicht für Nlgn4l Antikörper (C-Term) (ABIN7233051)

Target

Nlgn4l (NLGN4L) (Neuroligin 4-Like (NLGN4L))

Reaktivität

Maus

Wirt

  • 6
Maus

Klonalität

  • 6
Monoklonal

Konjugat

  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Nlgn4l Antikörper ist unkonjugiert

Applikation

  • 6
  • 6
  • 6
  • 6
Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (fixed cells) (IF/ICC)

Klon

S98-7
  • Bindungsspezifität

    AA 782-945, C-Term

    Verwendungszweck

    Anti-Neuroligin-4 Mouse Monoclonal Antibody

    Spezifität

    This antibody recognizes mouse Neuroligin-4. It does not cross-react with other Neuroligins.

    Kreuzreaktivität

    Maus, Ratte

    Immunogen

    Fusion protein corresponding to aa 782-945 (intracellular C-terminus) of mouse Neuroligin-4.

    Isotyp

    IgG1
  • Applikationshinweise

    Immunoblotting: use at 1-2 μg/mL. A band of ~125-130 kDa is detected.
    Immunofluorescence: use at 10 μg/mL.
    These are recommended concentrations.
    Enduser should determine optimal concentrations for their application.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Rekonstitution

    Dilute in PBS or medium that is identical to that used in the assay system.

    Konzentration

    1.0 mg/mL

    Buffer

    PBS, pH 7.4, 0.1 % sodium azide, 50 % glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    This product is stable for at least one (1) year at -20°C.
  • Target

    Nlgn4l (NLGN4L) (Neuroligin 4-Like (NLGN4L))

    Andere Bezeichnung

    Nlgn4l

    Hintergrund

    Neuroligin 4-like,Cell surface protein involved in cell-cell-interactions. Plays a role in the formation or maintenance of synaptic junctions via its interactions (via the extracellular domains) with neurexin family members. Plays a role in synaptic signal transmission. {PubMed:18434543, PubMed:21282647}.,Neuroligin-4 is a neuronal cell surface protein and a member of the type-B carboxylesterase- lipase protein family. Members of this family may act as splice site-specific ligands for beta- neurexins and may be involved in the formation and remodeling of central nervous system synapses. Neuroligin-4 interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants.,Cell membrane, Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane. Note=Detected at glycinergic postsynapses in retina. Detected on dendritic spines on cultured neurons.,Neuroligin-4, NL-4

    UniProt

    B0F2B4
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