Neuroligin 3 Antikörper (C-Term)

Produktnummer ABIN7233050

Der Maus Monoklonal anti-Neuroligin 3 Antikörper wird verwendet zum Nachweis von Neuroligin 3 in Proben von Ratte. Er wurde validiert für WB, IHC und IF/ICC.

Kurzübersicht für Neuroligin 3 Antikörper (C-Term) (ABIN7233050)

Target: Neuroligin 3 (NLGN3)

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Neuroligin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (fixed cells) (IF/ICC)

Klon: S110-29

Produktdetails anti-Neuroligin 3 Antikörper

Bindungsspezifität: AA 730-848, C-Term

Verwendungszweck: Anti-Neuroligin-3 Mouse Monoclonal Antibody

Spezifität: This antibody recognizes human, mouse and rat Neuroligin-3. It does not cross- react with Neuroligin-1, -2, or -4.

Kreuzreaktivität: Human, Maus, Ratte

Immunogen: Fusion protein corresponding to aa 730-848 (intracellular C-terminus) of rat Neuroligin- 3. This sequence is 99

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunoblotting: use at 1-5 μg/mL. A band of ~110 kDa is detected.
Immunofluorescence: use at 10 μg/mL.
These are recommended concentrations.
Endusers should determine optimal concentrations for their application.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Dilute in PBS or medium that is identical to that used in the assay system.

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 0.1 % sodium azide, 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: This product is stable for at least one (1) year at -20°C.

Details zu Neuroligin 3

Target: Neuroligin 3 (NLGN3)

Andere Bezeichnung: Nlgn3

Hintergrund: Neuroligin-3,Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system. {PubMed:17897391}.,Neuroligin-3 is a neuronal cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. It plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. It may also promote the initial formation of synapses and play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.,Cell membrane, Single-pass type I membrane protein. Cell junction, synapse. Note=Detected at both glutamatergic and GABAergic synapses.,Gliotactin homolog

UniProt: Q62889

Pathways: Synaptic Membrane