GABRD Antikörper (AA 15-34)

Produktnummer ABIN7233022

Dieses Maus Monoklonal-Antikörper erkennt spezifisch GABRD in WB und IF/ICC. Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für GABRD Antikörper (AA 15-34) (ABIN7233022)

Target: GABRD (GABA A Receptor delta (GABRD))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GABRD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (fixed cells) (IF/ICC)

Klon: S151-3

Produktdetails anti-GABRD Antikörper

Bindungsspezifität: AA 15-34

Verwendungszweck: Anti-δ GABA-A Receptor Mouse Monoclonal Antibody

Spezifität: This antibody recognizes mouse and rat Delta GABA-A receptor.

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Purified by Protein G affinity chromatography.

Immunogen: Synthetic peptide corresponding to aa 15-34 of rat Delta GABA-A receptor (accession no. P18506).

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Immunoblotting: use at 1-10 μg/mL. A band of ~55 kDa is detected.Immunohistochemistry and
Immunocytochemistry: use at 0.1-1 μg/mL
Immunofluorescence: use at 1-10 μg/mL
These are recommended concentrations. User should determine optimal concentrations for their application.
Positive control: Rat brain.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Dilute in PBS or medium that is identical to that used in the assay system.

Konzentration: Lot specific

Buffer: PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: This antibody is stable for at least one (1) year at -20°C.

Details zu GABRD

Target: GABRD (GABA A Receptor delta (GABRD))

Andere Bezeichnung: Gabrd

Hintergrund: γ-aminobutyric acid receptor subunit δ,GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.,GABA is the major inhibitory neuro- transmitter in the vertebrate brain. GABA receptors consist of five subunits that form a chloride ion channel. Subunit families alpha, beta, g, and delta have been studied extensively, e€ and epsilon have been identified recently. Studies of recombinant GABA receptors have shown that individual subunits and their subtypes confer different sensitivities to GABA receptor modulators. Subunit subtypes are differentially expressed throughout development and in different CNS regions, reducing the total number of possible isoforms that can be formed in different brain regions and in individual cells.,Cell junction, synapse, postsynaptic cell membrane, Multi-pass membrane protein. Cell membrane, Multi-pass membrane protein.,GABA(A receptor subunit δ

UniProt: P18506