CHGB Antikörper (C-Term)

Produktnummer ABIN7232896

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CHGB in WB. Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für CHGB Antikörper (C-Term) (ABIN7232896)

Target: CHGB (Chromogranin B (Secretogranin 1) (CHGB))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHGB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CHGB Antikörper

Bindungsspezifität: AA 641-655, C-Term

Verwendungszweck: Anti-Chromogranin B Rabbit Polyclonal Antibody

Spezifität: This antibody recognizes human, mouse, and rat chromogranin B.

Kreuzreaktivität: Human, Maus, Ratte

Immunogen: Synthetic peptide derived from the C-terminus (aa 641-655) of CgB (accession no. NP_001810. This sequence is identical in human, mouse, and rat CgB.

Anwendungsinformationen

Applikationshinweise: Immunoblotting: use at 0.1-1.0 μg/mL
These are recommended concentrations.
Enduser should determine optimal concentrations for their applications.Although the predicted mw of CgB is ~76 kDa, the highly acidic nature of CgB causes it to run at a higher mw in SDS-PAGE.
Immunohistochemistry: use at 1-5 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Dilute in PBS or medium that is identical to that used in the assay system.

Konzentration: Lot specific

Buffer: PBS, pH 7.4

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: This antibody is stable for at least one (1) year at -20°C to -70°C. Avoid multiple freeze-thaw cycles.

Details zu CHGB

Target: CHGB (Chromogranin B (Secretogranin 1) (CHGB))

Andere Bezeichnung: CHGB

Hintergrund: Secretogranin-1,Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.,Chromogranin B (CgB, secretogranin I) is a secretory granule matrix protein expressed in a wide variety of endocrine cells and neurons where it may have both extracellular and intracellular functions. Extracellular roles for CgB are dependent on its proteolytic processing within secretory granules to form smaller peptides that may have a role in the neuroendocrine/sympathoadrenal stress response to systemic infection, and CgB fragments may also have an autocrine inhibitory role in the release of co-stored hormones, such as insulin.,Secreted. Note=Neuroendocrine and endocrine secretory granules.,Chromogranin-B, CgB, Secretogranin I, SgI [Cleaved into: PE-11, GAWK peptide, CCB peptide]

UniProt: P05060