Glutathione Reductase Antikörper (AA 44-522)

Produktnummer ABIN7232834

Der Maus Monoklonal anti-Glutathione Reductase Antikörper wird verwendet zum Nachweis von Glutathione Reductase in Proben von Human. Er wurde validiert für WB und ELISA.

Kurzübersicht für Glutathione Reductase Antikörper (AA 44-522) (ABIN7232834)

Target: Glutathione Reductase (GSR)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Glutathione Reductase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 2A2-1B7

Produktdetails anti-Glutathione Reductase Antikörper

Bindungsspezifität: AA 44-522

Verwendungszweck: Anti-Glutathione Reductase Mouse Monoclonal Antibody

Spezifität: These antibodies recognize human glutathione reductase. They do not cross-react with yeast glutathione reductase.

Kreuzreaktivität: Human

Immunogen: Recombinant human glutathione reductase purified from E. coli expressing the human glutathione reductase gene (aa 44-522).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: Titration of glutathione reductase MAbs with glutathione reductase at 3 μg/mL on the wells.ELISA Pairs: Both of these antibodies function as capture and detection antibodies at 1 μg/mL.
Immunoblotting: use at 0.5-1.0 μg/mL. A band of ~57 kDa is detected.
These are recommended concentrations.
Endusers should determine optimal concentrations for their applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Dilute in PBS or medium that is identical to that used in the assay system.

Konzentration: Lot specific

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: These antibodies are stable for at least one (1) year at -20°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.

Details zu Glutathione Reductase

Target: Glutathione Reductase (GSR)

Andere Bezeichnung: GSR

Hintergrund: Glutathione reductase, mitochondrial,Maintains high levels of reduced glutathione in the cytosol.,Glutathione reductase, also known as glutathione-disulfide reductase, is an enzyme that in humans is encoded by the GSR gene. Glutathione reductase catalyzes the reduction of glutathione disulfide to the sulfhydryl form glutathione (GSH), which is a critical molecule in resisting oxidative stress and maintaining the reducing environment of the cell. The importance of the glutathione pathway and enzymes that affect it is gaining an increased level of attention. Although glutathione reductase has been an attractive target for many pharmaceuticals, there have been no successful glutathione reductase related therapeutic compounds created to date.,[Isoform Mitochondrial]: Mitochondrion., [Isoform Cytoplasmic]: Cytoplasm.,GR, GRase, EC 1.8.1.7

NCBI Accession: NP_000628

UniProt: P00390

Pathways: Thyroid Hormone Synthesis, Cell RedoxHomeostasis