ZFYVE19 Antikörper (AA 280-360)

Produktnummer ABIN7217550

Der Kaninchen Polyklonal anti-ZFYVE19 Antikörper wird verwendet zum Nachweis von ZFYVE19 in Proben von Human und Maus. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für ZFYVE19 Antikörper (AA 280-360) (ABIN7217550)

Target: ZFYVE19 (Zinc Finger, FYVE Domain Containing 19 (ZFYVE19))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZFYVE19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-ZFYVE19 Antikörper

Bindungsspezifität: AA 280-360

Verwendungszweck: Rabbit Anti-ZFYVE19 Polyclonal Antibody

Spezifität: ZFYVE19 Polyclonal Antibody detects endogenous levels of ZFYVE19 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human ZFYVE19 at AA range: 280-360

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ZFYVE19

Target: ZFYVE19 (Zinc Finger, FYVE Domain Containing 19 (ZFYVE19))

Andere Bezeichnung: ZFYVE19

Hintergrund: ZFYVE19, MPFYVE, Zinc finger FYVE domain-containing protein 19, MLL partner containing FYVE domainZinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZFYVE19 (zinc finger, FYVE domain containing 19), also known as MPFYVE (MLL partner containing FYVE domain), is a 471 amino acid protein that contains one FYVE-type zinc finger. Expressed in heart, brain, kidney, skeletal muscle and liver, ZFYVE19 may participate in transcriptional regulation events within the cell. Defects in the gene encoding ZFYVE19 are associated with acute myeloblastic leukemia (AML), a rapidly progressing cancer of the myeloid line of white blood cells that is characterized by fever, anemia, bone pain, shortness of breath and frequent infections. Three isoforms of ZFYVE19 exist due to alternative splicing events.

Molekulargewicht: 50kD

Gen-ID: 84936

UniProt: Q96K21