TSHZ3 Antikörper

Produktnummer ABIN7231940

Der Kaninchen Polyklonal anti-TSHZ3 Antikörper (ABIN7231940) detektiert spezifisch TSHZ3 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für TSHZ3 Antikörper (ABIN7231940)

Target: TSHZ3 (Teashirt Zinc Finger Homeobox 3 (TSHZ3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSHZ3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TSHZ3 Antikörper

Verwendungszweck: Rabbit Anti-TSH3 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of TSH3 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TSH3 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu TSHZ3

Target: TSHZ3 (Teashirt Zinc Finger Homeobox 3 (TSHZ3))

Andere Bezeichnung: TSH3

Hintergrund: Teashirt homolog 3, Zinc finger protein 537TSHZ3 (Teashirt Zinc Finger Homeobox 3) encodes a zinc-finger transcription factor that regulates smooth muscle cell differentiation in the developing urinary tract. Consistent with this role, mice in which TSHZ3 has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis. The encoded transcription factor comprises a gene silencing complex that inhibits caspase expression. Reduced expression of TSHZ3 and consequent caspase upregulation may be correlated with progression of Alzheimer's disease in human patients. TSHZ3 is a Protein Coding gene. Diseases associated with TSHZ3 include Hydronephrosis and Endemic Goiter.

Molekulargewicht: 118kD

Gen-ID: 57616

UniProt: Q63HK5

Pathways: Regulation of Muscle Cell Differentiation