TSHZ3 Antikörper
Kurzübersicht für TSHZ3 Antikörper (ABIN7231940)
Target
Alle TSHZ3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- TSH3 Polyclonal Antibody
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Spezifität
- The antibody detects endogenous levels of TSH3 protein
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Aufreinigung
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human TSH3 protein
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Kommentare
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Primary Antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TSHZ3 (Teashirt Zinc Finger Homeobox 3 (TSHZ3))
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Andere Bezeichnung
- TSH3
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Hintergrund
- Rabbit Anti-TSH3 Polyclonal Antibody,Teashirt homolog 3, Zinc finger protein 537,TSHZ3 (Teashirt Zinc Finger Homeobox 3) encodes a zinc-finger transcription factor that regulates smooth muscle cell differentiation in the developing urinary tract. Consistent with this role, mice in which TSHZ3 has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis. The encoded transcription factor comprises a gene silencing complex that inhibits caspase expression. Reduced expression of TSHZ3 and consequent caspase upregulation may be correlated with progression of Alzheimer's disease in human patients. TSHZ3 is a Protein Coding gene. Diseases associated with TSHZ3 include Hydronephrosis and Endemic Goiter.,TSH3
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Molekulargewicht
- observerd band 118kDa
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Gen-ID
- 57616
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UniProt
- Q63HK5
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Pathways
- Regulation of Muscle Cell Differentiation
Target
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