ZBTB33 Antikörper (AA 100-180)
Kurzübersicht für ZBTB33 Antikörper (AA 100-180) (ABIN7229226)
Target
Alle ZBTB33 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 100-180
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Verwendungszweck
- Rabbit Anti-KAISO Polyclonal Antibody
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Spezifität
- The antibody detects endogenous levels of KAISO protein
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from part region of human KAISO protein at AA range: 100-180
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Haltbarkeit
- 12 months
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- ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))
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Andere Bezeichnung
- KAISO
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Hintergrund
- Transcriptional regulator Kaiso Zinc finger and BTB domain-containing protein 33ZBTB33 (Zinc Finger And BTB Domain Containing 33) encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. ZBTB33 is a Protein Coding gene. Diseases associated with ZBTB33 include Epithelial Malignant Thymoma and Dendritic Cell Thymoma. Among its related pathways are Wnt Signaling Pathway and Pluripotency.
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Molekulargewicht
- 73kD
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Gen-ID
- 10009
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UniProt
- Q86T24
Target
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