Vimentin Antikörper (AA 20-90)
Kurzübersicht für Vimentin Antikörper (AA 20-90) (ABIN7226806)
Target
Alle Vimentin (VIM) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 20-90
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Verwendungszweck
- Vimentin (Phospho-Tyr38) Polyclonal Antibody
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Spezifität
- The antibody detects endogenous Vimentin (Phospho-Tyr38) protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthetic peptide from human protein at AA range: 20-90
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:10000), ELISA (1:10000).
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Kommentare
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Primary Antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Vimentin (VIM)
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Andere Bezeichnung
- Vimentin
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Hintergrund
- Rabbit Anti-Vimentin (Phospho-Tyr38) Polyclonal Antibody,VIM,VIM (vimentin) encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by VIM is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in VIM causes a dominant, pulverulent cataract.,vimentin
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Molekulargewicht
- observerd band 51kDa
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Gen-ID
- 7431
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UniProt
- P08670
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Pathways
- Caspase Kaskade in der Apoptose
Target
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