VAV3 Antikörper
Kurzübersicht für VAV3 Antikörper (ABIN7218992)
Target
Alle VAV3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Vav3 Polyclonal Antibody
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Spezifität
- Vav3 Polyclonal Antibody detects endogenous levels of Vav3 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from human Vav3 around the non-phosphorylation site of Y173
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.
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Kommentare
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Primary Antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- VAV3 (Vav 3 Oncogene (VAV3))
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Andere Bezeichnung
- Vav3
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Hintergrund
- Rabbit Anti-Vav3 Polyclonal Antibody,VAV3, Guanine nucleotide exchange factor VAV3, VAV-3,VAV3 is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.,Guanine nucleotide exchange factor VAV3
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Molekulargewicht
- observerd band 98kDa
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Gen-ID
- 10451
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UniProt
- Q9UKW4
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung
Target
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