UVRAG Antikörper

Produktnummer ABIN7232056

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch UVRAG in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für UVRAG Antikörper (ABIN7232056)

Target: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UVRAG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-UVRAG Antikörper

Verwendungszweck: Rabbit Anti-UVRAG Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of UVRAG protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human UVRAG protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu UVRAG

Target: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Andere Bezeichnung: UVRAG

Hintergrund: UV radiation resistance-associated gene protein, p63UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. UV Radiation Resistance Associated activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.

Molekulargewicht: 76kD

Gen-ID: 7405

UniProt: Q9P2Y5