UBTF Antikörper

Produktnummer ABIN7224858

Der Kaninchen Polyklonal Anti-UBTF Antikörper wurde für WB und ELISA validiert. Er ist geeignet, UBTF in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für UBTF Antikörper (ABIN7224858)

Target: UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBTF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-UBTF Antikörper

Verwendungszweck: UBF Polyclonal Antibody

Spezifität: UBF Polyclonal Antibody detects endogenous levels of UBF protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human UBF around the non-phosphorylation site of S484

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu UBTF

Target: UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))

Andere Bezeichnung: UBF

Hintergrund: Rabbit Anti-UBF Polyclonal Antibody,UBTF, UBF, UBF1, Nucleolar transcription factor 1, Autoantigen NOR-90, Upstream-binding factor 1, UBF-1,UBTF (upstream binding transcription factor, RNA polymerase I) encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for UBTF. Pseudogenes of UBTF are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.,Nucleolar transcription factor 1

Molekulargewicht: observerd band 89kDa

Gen-ID: 7343

UniProt: P17480