UBTF Antikörper (pSer484)

Produktnummer ABIN7224856

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch UBTF in WB, ELISA und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für UBTF Antikörper (pSer484) (ABIN7224856)

Target: UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBTF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-UBTF Antikörper

Bindungsspezifität: pSer484

Verwendungszweck: UBF (phospho Ser484) Polyclonal Antibody

Spezifität: Phospho-UBF (S484) Polyclonal Antibody detects endogenous levels of UBF protein only when phosphorylated at S484.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human UBF Phospho-Ser484

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu UBTF

Target: UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))

Andere Bezeichnung: UBF

Hintergrund: Rabbit Anti-UBF (phospho Ser484) Polyclonal Antibody,UBTF, UBF, UBF1, Nucleolar transcription factor 1, Autoantigen NOR-90, Upstream-binding factor 1, UBF-1,UBTF (upstream binding transcription factor, RNA polymerase I) encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for UBTF. Pseudogenes of UBTF are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.,Nucleolar transcription factor 1

Molekulargewicht: observerd band 85kDa

Gen-ID: 7343

UniProt: P17480