UNC5D Antikörper (AA 160-240)

Produktnummer ABIN7232044

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch UNC5D in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für UNC5D Antikörper (AA 160-240) (ABIN7232044)

Target: UNC5D (Unc-5 Homolog D (UNC5D))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UNC5D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-UNC5D Antikörper

Bindungsspezifität: AA 160-240

Verwendungszweck: Rabbit Anti-UNC5D Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of UNC5D protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human UNC5D protein at AA range: 160-240

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu UNC5D

Target: UNC5D (Unc-5 Homolog D (UNC5D))

Andere Bezeichnung: UNC5D

Hintergrund: Netrin receptor UNC5D, Protein unc-5 homolog 4, Protein unc-5 homolog DReceptor for the netrin NTN4 that promotes neuronal cell survival. Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. May play a role in apoptosis in response to DNA damage. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed: 24519068). Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell.

Molekulargewicht: 104kD

Gen-ID: 137970

UniProt: Q6UXZ4