ULBP3 Antikörper

Produktnummer ABIN7229880

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ULBP3 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ULBP3 Antikörper (ABIN7229880)

Target: ULBP3 (UL16 Binding Protein 3 (ULBP3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ULBP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ULBP3 Antikörper

Verwendungszweck: Rabbit Anti-N2DL3 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of N2DL3 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human N2DL3 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ULBP3

Target: ULBP3 (UL16 Binding Protein 3 (ULBP3))

Andere Bezeichnung: N2DL3

Hintergrund: UL16-binding protein 3, ALCAN-gamma, NKG2D ligand 3, N2DL-3, NKG2DL3, Retinoic acid early transcript 1NUL16 Binding Protein 3 encoded by ULBP3 is one of several related ligands of the KLRK1/NKG2D receptor, which is found in primary NK cells. Binding of these ligands to the receptor activates several signal transduction pathways, including the JAK2, STAT5 and ERK pathways. The encoded protein is expressed solubly and on the surface of many tumor cells, making it potentially an important target for therapeutics.

Molekulargewicht: 26kD

Gen-ID: 79465

UniProt: Q9BZM4

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process