ULBP2 Antikörper

Produktnummer ABIN7229878

Der Kaninchen Polyklonal anti-ULBP2 Antikörper (ABIN7229878) detektiert spezifisch ULBP2 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ULBP2 Antikörper (ABIN7229878)

Target: ULBP2 (UL16 Binding Protein 2 (ULBP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ULBP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ULBP2 Antikörper

Verwendungszweck: Rabbit Anti-N2DL2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of N2DL2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human N2DL2 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ULBP2

Target: ULBP2 (UL16 Binding Protein 2 (ULBP2))

Andere Bezeichnung: N2DL2

Hintergrund: UL16-binding protein 2, ALCAN-alpha, NKG2D ligand 2, N2DL-2, NKG2DL2, Retinoic acid early transcript 1HULBP2 encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. ULBP2 is located in a cluster of multiple MHC class I-related genes on chromosome 6. ULBP2 (UL16 Binding Protein 2) is a Protein Coding gene. Among its related pathways are Immune response Role of DAP12 receptors in NK cells and p53 Pathway (RnD).

Molekulargewicht: 27kD

Gen-ID: 80328

UniProt: Q9BZM5