UBXN11 Antikörper (AA 100-180)

Produktnummer ABIN7225846

Der Kaninchen Polyklonal anti-UBXN11 Antikörper wird verwendet zum Nachweis von UBXN11 in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA, IHC, WB und IF.

Kurzübersicht für UBXN11 Antikörper (AA 100-180) (ABIN7225846)

Target: UBXN11 (UBX Domain Protein 11 (UBXN11))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBXN11 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-UBXN11 Antikörper

Bindungsspezifität: AA 100-180

Verwendungszweck: Rabbit Anti-Socius Polyclonal Antibody

Spezifität: Socius Polyclonal Antibody detects endogenous levels of Socius protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Socius at AA range: 100-180

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu UBXN11

Target: UBXN11 (UBX Domain Protein 11 (UBXN11))

Andere Bezeichnung: Socius

Hintergrund: UBXN11, SOC, UBXD5, PP2243, UBX domain-containing protein 11, Colorectal tumor-associated antigen COA-1, Socius, UBX domain-containing protein 5UBXN11 (UBX domain protein 11) encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of UBXN11 contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1. and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for UBXN11.

Molekulargewicht: 57kD

Gen-ID: 91544

UniProt: Q5T124