TUSC5 Antikörper (AA 10-90)

Produktnummer ABIN7221268

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch TUSC5 in ELISA, WB und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TUSC5 Antikörper (AA 10-90) (ABIN7221268)

Target: TUSC5 (Tumor Suppressor Candidate 5 (TUSC5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TUSC5 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-TUSC5 Antikörper

Bindungsspezifität: AA 10-90

Verwendungszweck: LOST1 Polyclonal Antibody

Spezifität: LOST1 Polyclonal Antibody detects endogenous levels of LOST1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human LOST1 at AA range: 10-90

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu TUSC5

Target: TUSC5 (Tumor Suppressor Candidate 5 (TUSC5))

Andere Bezeichnung: LOST1

Hintergrund: Rabbit Anti-LOST1 Polyclonal Antibody,TUSC5, IFITMD3, LOST1, Tumor suppressor candidate 5, Dispanin subfamily B member 1, DSPB1, Interferon-induced transmembrane domain-containing protein D3, Protein located at seventeen-p-thirteen point three 1,TUSC5 (tumor suppressor candidate 5), also known as protein located at seventeen-p-thirteen point three 1, LOST1 or IFITMD3 (interferon-induced transmembrane domain-containing protein D3), is a 177 amino acid multi-pass membrane protein that belongs to the CD225 family. Thought to play a role in fat metabolism, TUSC5 is highly expressed in mammary gland, heart, smooth muscle, skeletal muscle and stomach, with lower levels found in lung and brain. The gene encoding TUSC5 maps to human chromosome 17, which comprises over 2. % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, and is liked to predisposition of cancers of the ovary, colon, prostate gland and fallopian tubes.,Tumor suppressor candidate 5

Molekulargewicht: observerd band 22kDa

Gen-ID: 286753

UniProt: Q8IXB3