TSEN2 Antikörper
Kurzübersicht für TSEN2 Antikörper (ABIN7231306)
Target
Alle TSEN2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- SEN2 Polyclonal Antibody
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Spezifität
- The antibody detects endogenous levels of SEN2 protein
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Aufreinigung
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human SEN2 protein
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Kommentare
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Primary Antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))
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Andere Bezeichnung
- SEN2
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Hintergrund
- Rabbit Anti-SEN2 Polyclonal Antibody,tRNA-splicing endonuclease subunit Sen2, tRNA-intron endonuclease Sen2, HsSen2,TSEN2 (TRNA Splicing Endonuclease Subunit 2) is a Protein Coding gene. Diseases associated with TSEN2 include Pontocerebellar Hypoplasia Type 2B and Pontocerebellar Hypoplasia, Type 2E. Among its related pathways are Gene Expression and tRNA processing. TSEN2 encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in TSEN2 have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for TSEN2.,SEN2
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Molekulargewicht
- observerd band 51kDa
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Gen-ID
- 80746
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UniProt
- Q8NCE0
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Pathways
- Nuclear Receptor Transcription Pathway, Regulation of Lipid Metabolism by PPARalpha
Target
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