TMEM201 Antikörper

Produktnummer ABIN7229128

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TMEM201 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für TMEM201 Antikörper (ABIN7229128)

Target: TMEM201 (Transmembrane Protein 201 (TMEM201))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMEM201 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TMEM201 Antikörper

Verwendungszweck: Rabbit Anti-IMA1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of IMA1 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human IMA1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu TMEM201

Target: TMEM201 (Transmembrane Protein 201 (TMEM201))

Andere Bezeichnung: IMA1

Hintergrund: Importin subunit alpha-5, Karyopherin subunit alpha-1, Nucleoprotein interactor 1, NPI-1, RAG cohort protein 2, SRP1-betaKPNA1 (Karyopherin Subunit Alpha 1) is a Protein Coding gene. Diseases associated with KPNA1 include Influenza and Ovarian Endodermal Sinus Tumor. Among its related pathways are HIV Life Cycle and Apoptosis induced DNA fragmentation. The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by KPNA1 belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase.

Molekulargewicht: 59kD

Gen-ID: 3836

UniProt: P52294