TTF2 Antikörper

Produktnummer ABIN7231960

Der Kaninchen Polyklonal anti-TTF2 Antikörper wird verwendet zum Nachweis von TTF2 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für TTF2 Antikörper (ABIN7231960)

Target: TTF2 (Transcription Termination Factor, RNA Polymerase II (TTF2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TTF2 Antikörper

Verwendungszweck: Rabbit Anti-TTF2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of TTF2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TTF2 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu TTF2

Target: TTF2 (Transcription Termination Factor, RNA Polymerase II (TTF2))

Andere Bezeichnung: TTF2

Hintergrund: Transcription termination factor 2, Lodestar homolog, RNA polymerase II termination factor, Transcription release factor 2, F2, HuF2TTF2 (Transcription Termination Factor 2) is a Protein Coding gene. Among its related pathways are Insulin secretion and Human Thyroid Stimulating Hormone (TSH) signaling pathway. TTF2 encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing.

Molekulargewicht: 127kD

Gen-ID: 8458

UniProt: Q9UNY4

Pathways: Thyroid Hormone Synthesis