TLE1/2/3/4 (AA 721-770) Antikörper

Produktnummer ABIN7226814

Der Kaninchen Polyklonal anti-TLE1/2/3/4 Antikörper wird verwendet zum Nachweis von TLE1/2/3/4 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für TLE1/2/3/4 (AA 721-770) Antikörper (ABIN7226814)

Target: TLE1/2/3/4

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails

Bindungsspezifität: AA 721-770

Verwendungszweck: Rabbit Anti-TLE1/2/3/4 Polyclonal Antibody

Spezifität: TLE1/2/3/4 Polyclonal Antibody detects endogenous levels of TLE1/2/3/4.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from TLE1/2/3/4 at AA range: 721-770

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Antigendetails

Target: TLE1/2/3/4

Hintergrund: Similar to transducin-like enhancer of split 1/2/3/4Transducin-like enhancer of split proteins (TLE1, TLE2, TLE3, TLE4, and TLE6) are mammalian homologs of Drosophila Groucho. TLEs contain several WD-repeats implicated in protein-protein interaction. TLEs are transcriptional co-repressors that bind to many transcription factors such as LEF1, Runx1, Oct-1, hepatocyte nuclear factor 3-β as well as histone H3. TLEs are differentially expressed during animal development and may have overlapping as well as distinct functions.

Molekulargewicht: 90kD

Gen-ID: 7088

UniProt: Q04724, Q04725, Q04726, Q04727