TSH receptor Antikörper (AA 280-360)

Produktnummer ABIN7231944

Der Kaninchen Polyklonal anti-TSH receptor Antikörper (ABIN7231944) detektiert spezifisch TSH receptor in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für TSH receptor Antikörper (AA 280-360) (ABIN7231944)

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSH receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TSH receptor Antikörper

Bindungsspezifität: AA 280-360

Verwendungszweck: Rabbit Anti-TSHR Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of TSHR protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TSHR protein at AA range: 280-360

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu TSH receptor

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Andere Bezeichnung: TSHR

Hintergrund: Thyrotropin receptor, Thyroid-stimulating hormone receptor, TSH-RReceptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed: 11847099, PubMed: 12045258). Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2: GPHB5) or thyrostimulin (PubMed: 12045258). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed: 11847099). Plays a central role in controlling thyroid cell metabolism (By similarity).

Molekulargewicht: 84kD

Gen-ID: 7253

UniProt: P16473

Pathways: Thyroid Hormone Synthesis