TSH receptor Antikörper (AA 280-360)

Produktnummer ABIN7231944

Der Kaninchen Polyklonal anti-TSH receptor Antikörper (ABIN7231944) detektiert spezifisch TSH receptor in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für TSH receptor Antikörper (AA 280-360) (ABIN7231944)

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSH receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TSH receptor Antikörper

Bindungsspezifität: AA 280-360

Verwendungszweck: TSHR Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of TSHR protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human TSHR protein at AA range: 280-360

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu TSH receptor

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Andere Bezeichnung: TSHR

Hintergrund: Rabbit Anti-TSHR Polyclonal Antibody,Thyrotropin receptor, Thyroid-stimulating hormone receptor, TSH-R,Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed: 11847099, PubMed: 12045258). Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2: GPHB5) or thyrostimulin (PubMed: 12045258). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed: 11847099). Plays a central role in controlling thyroid cell metabolism (By similarity).,TSHR

Molekulargewicht: observerd band 84kDa

Gen-ID: 7253

UniProt: P16473

Pathways: Thyroid Hormone Synthesis