TRIP12 Antikörper (AA 950-1030)

Produktnummer ABIN7231912

Der Kaninchen Polyklonal anti-TRIP12 Antikörper (ABIN7231912) detektiert spezifisch TRIP12 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für TRIP12 Antikörper (AA 950-1030) (ABIN7231912)

Target: TRIP12 (Thyroid Hormone Receptor Interactor 12 (TRIP12))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIP12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TRIP12 Antikörper

Bindungsspezifität: AA 950-1030

Verwendungszweck: Rabbit Anti-TRIPC Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of TRIPC protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TRIPC protein at AA range: 950-1030

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu TRIP12

Target: TRIP12 (Thyroid Hormone Receptor Interactor 12 (TRIP12))

Andere Bezeichnung: TRIPC

Hintergrund: E3 ubiquitin-protein ligase TRIP12, E3 ubiquitin-protein ligase for Arf, ULF, HECT-type E3 ubiquitin transferase TRIP12, Thyroid receptor-interacting protein 12, TR-interacting protein 12, TRIP-12TRIP12 (Thyroid Hormone Receptor Interactor 12) is a Protein Coding gene. Diseases associated with TRIP12 include Non-Syndromic Intellectual Disability and Chronic Dacryocystitis. Among its related pathways are Class I MHC mediated antigen processing and presentation and Ubiquitin mediated proteolysis. The protein encoded by TRIP12 is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53.

Molekulargewicht: 219kD

Gen-ID: 9320

UniProt: Q14669

Pathways: Nuclear Hormone Receptor Binding