TRIP12 Antikörper (AA 950-1030)

Produktnummer ABIN7231912

Dieser Anti-TRIP12 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von TRIP12 in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für TRIP12 Antikörper (AA 950-1030) (ABIN7231912)

Target: TRIP12 (Thyroid Hormone Receptor Interactor 12 (TRIP12))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIP12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TRIP12 Antikörper

Bindungsspezifität: AA 950-1030

Verwendungszweck: TRIPC Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of TRIPC protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human TRIPC protein at AA range: 950-1030

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu TRIP12

Target: TRIP12 (Thyroid Hormone Receptor Interactor 12 (TRIP12))

Andere Bezeichnung: TRIPC

Hintergrund: Rabbit Anti-TRIPC Polyclonal Antibody,E3 ubiquitin-protein ligase TRIP12, E3 ubiquitin-protein ligase for Arf, ULF, HECT-type E3 ubiquitin transferase TRIP12, Thyroid receptor-interacting protein 12, TR-interacting protein 12, TRIP-12,TRIP12 (Thyroid Hormone Receptor Interactor 12) is a Protein Coding gene. Diseases associated with TRIP12 include Non-Syndromic Intellectual Disability and Chronic Dacryocystitis. Among its related pathways are Class I MHC mediated antigen processing and presentation and Ubiquitin mediated proteolysis. The protein encoded by TRIP12 is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53.,TRIPC

Molekulargewicht: observerd band 219kDa

Gen-ID: 9320

UniProt: Q14669

Pathways: Nuclear Hormone Receptor Binding