Thimet Oligopeptidase 1 Antikörper

Produktnummer ABIN7231786

Der Kaninchen Polyklonal anti-Thimet Oligopeptidase 1 Antikörper (ABIN7231786) detektiert spezifisch Thimet Oligopeptidase 1 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Thimet Oligopeptidase 1 Antikörper (ABIN7231786)

Target: Thimet Oligopeptidase 1 (THOP1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Thimet Oligopeptidase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Thimet Oligopeptidase 1 Antikörper

Verwendungszweck: Rabbit Anti-THOP1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of THOP1 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human THOP1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Thimet Oligopeptidase 1

Target: Thimet Oligopeptidase 1 (THOP1)

Andere Bezeichnung: THOP1

Hintergrund: Thimet oligopeptidase, Endopeptidase 24.15, MP78Thimet Oligopeptidase 1 encoded by THOP1 is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. Thimet Oligopeptidase 1 also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. THOP1 (Thimet Oligopeptidase 1) is a Protein Coding gene. Among its related pathways are African trypanosomiasis and ACE Inhibitor Pathway, Pharmacodynamics.

Molekulargewicht: 75kD

Gen-ID: 7064

UniProt: P52888