Tenascin N Antikörper

Produktnummer ABIN7231754

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Tenascin N in ELISA und WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Tenascin N Antikörper (ABIN7231754)

Target: Tenascin N (TNN)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tenascin N Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-Tenascin N Antikörper

Verwendungszweck: Rabbit Anti-TENN Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of TENN protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TENN protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Tenascin N

Target: Tenascin N (TNN)

Andere Bezeichnung: TENN

Hintergrund: Tenascin-N, TN-N, Tenascin-W, TN-WTNN (Tenascin N) is a Protein Coding gene. Diseases associated with TNN include Adhesive Otitis Media and Chronic Purulent Otitis Media. Among its related pathways are ECM proteoglycans and Focal Adhesion. Extracellular matrix protein that seems to be a ligand for ITGA8: ITGB1, ITGAV: ITGB1 and ITGA4: ITGB1. Involved in neurite outgrowth and cell migration in hippocampal explants. During endochondral bone formation, inhibits proliferation and differentiation of proteoblasts mediated by canonical WNT signaling. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells. Expressed in most mammary tumors, may facilitate tumorigenesis by supporting the migratory behavior of breast cancer cells.

Molekulargewicht: 142kD

Gen-ID: 63923

UniProt: Q9UQP3

Pathways: ACE Inhibitor Pathway