TCF4/12 (AA 550-630) Antikörper

Produktnummer ABIN7217260

Der Kaninchen-Polyklonal Anti-TCF4/12-Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet zum Nachweis von TCF4/12 in Proben aus Human, Maus und Ratte. }

Kurzübersicht für TCF4/12 (AA 550-630) Antikörper (ABIN7217260)

Target: TCF4/12

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails

Bindungsspezifität: AA 550-630

Verwendungszweck: TCF-4/12 Polyclonal Antibody

Spezifität: TCF-4/12 Polyclonal Antibody detects endogenous levels of TCF-4/12 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human TCF-4/12 at AA range: 550-630

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Antigendetails

Target: TCF4/12

Andere Bezeichnung: TCF-4/12

Hintergrund: Rabbit Anti-TCF-4/12 Polyclonal Antibody,TCF4, BHLHB19, ITF2, SEF2, Transcription factor 4, TCF-4, Class B basic helix-loop-helix protein 19, bHLHb19, Immunoglobulin transcription factor 2, ITF-2, SL3-3 enhancer factor 2, SEF-2, TCF12, BHLHB20, HEB, HTF4, Transcription factor 12,TCF4 encodes transcription factor 4, a basic helix-loop-helix transcription factor. The Transcription factor 4 recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described.,Transcription factor 4

Molekulargewicht: observerd band 60kDa

Gen-ID: 6925, 6938