tau Antikörper (acLys174)

Produktnummer ABIN7231708

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch tau in WB, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für tau Antikörper (acLys174) (ABIN7231708)

Target: tau (tau Protein)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser tau Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-tau Antikörper

Bindungsspezifität: acLys174

Verwendungszweck: Rabbit Anti-Tau (Acetyl Lys174) Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of Tau when Acetyl occurs at Lys174

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human Tau (Acetyl Lys174) protein at AA range: 174

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IF/ICC1:100-500,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu tau

Target: tau (tau Protein)

Andere Bezeichnung: Tau

Hintergrund: Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tauMAPT encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. MAPT (Microtubule Associated Protein Tau) is a Protein Coding gene. Diseases associated with MAPT include Pick Disease and Supranuclear Palsy, Progressive. Among its related pathways are Alzheimers Disease Pathway and Reelin signaling pathway.

Molekulargewicht: 50-85kD

Gen-ID: 4137

UniProt: P10636