TAO Kinase 3 Antikörper (AA 500-580)

Produktnummer ABIN7215504

Dieser Anti-TAO Kinase 3 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von TAO Kinase 3 in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für TAO Kinase 3 Antikörper (AA 500-580) (ABIN7215504)

Target: TAO Kinase 3 (TAOK3)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAO Kinase 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TAO Kinase 3 Antikörper

Bindungsspezifität: AA 500-580

Verwendungszweck: JIK Polyclonal Antibody

Spezifität: JIK Polyclonal Antibody detects endogenous levels of JIK protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human JIK at AA range: 500-580

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu TAO Kinase 3

Target: TAO Kinase 3 (TAOK3)

Andere Bezeichnung: JIK

Hintergrund: Rabbit Anti-JIK Polyclonal Antibody,TAOK3, DPK, JIK, KDS, MAP3K18, Serine/threonine-protein kinase TAO3, Cutaneous T-cell lymphoma-associated antigen HD-CL-09, CTCL-associated antigen HD-CL-09, Dendritic cell-derived protein kinase, JNK/SAPK-inhibitory kinase, Jun kinase-inhi,TAOK3 is a Protein Coding gene. Serine/threonine-protein kinase TAO3 acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF). Diseases associated with TAOK3 include kabuki syndrome 1. Among its related pathways are MAPK signaling pathway and p38 MAPK signaling pathway (Pathway Interaction Database). Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is TAOK1.,serine threonine-protein kinase TAO3

Molekulargewicht: observerd band 110kDa

Gen-ID: 51347

UniProt: Q9H2K8