Der Kaninchen Polyklonal anti-SV2B Antikörper (ABIN7231600) detektiert spezifisch SV2B in WB und ELISA.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.
SV2B
Reaktivität: Human, Maus
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
Cy5.5
Applikationshinweise
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
Konservierungsmittel
ProClin
Vorsichtsmaßnahmen
This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Haltbarkeit
12 months
Target
SV2B
(Synaptic Vesicle Glycoprotein 2B (SV2B))
Andere Bezeichnung
SV2B
Hintergrund
Synaptic vesicle glycoprotein 2BSV2B encodes a member of the synaptic vesicle proteins 2 (SV2) family and major facilitator superfamily of proteins. This protein and other members of the family are localized to synaptic vesicles and may function in the regulation of vesicle trafficking and exocytosis. Studies in mice suggest that the encoded protein may act as a protein receptor for botulinum neurotoxin E in neurons, and that this protein may be important for the integrity of the glomerular filtration barrier. SV2B shows reduced expression in areas of synaptic loss in the hippocampus of human temporal lobe epilepsy patients.