ST5 Antikörper (AA 380-460)

Produktnummer ABIN7217128

Dieser Anti-ST5 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von ST5 in WB und ELISA. Geeignet für Human und Maus.

Kurzübersicht für ST5 Antikörper (AA 380-460) (ABIN7217128)

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ST5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ST5 Antikörper

Bindungsspezifität: AA 380-460

Verwendungszweck: ST5 Polyclonal Antibody

Spezifität: ST5 Polyclonal Antibody detects endogenous levels of ST5 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human ST5 at AA range: 380-460

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu ST5

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Andere Bezeichnung: ST5

Hintergrund: Rabbit Anti-ST5 Polyclonal Antibody,ST5, DENND2B, HTS1, Suppression of tumorigenicity 5 protein, DENN domain-containing protein 2B, HeLa tumor suppression 1,ST5 was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. Suppression of tumorigenicity 5 protein encoded by ST5 contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.,Suppression of tumorigenicity 5 protein

Molekulargewicht: observerd band 126kDa

Gen-ID: 6764

UniProt: P78524