SP100 Antikörper (AA 250-330)

Produktnummer ABIN7224440

Der Kaninchen Polyklonal anti-SP100 Antikörper wird verwendet zum Nachweis von SP100 in Proben von Human und Maus. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für SP100 Antikörper (AA 250-330) (ABIN7224440)

Target: SP100 (SP100 Nuclear Antigen (SP100))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SP100 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-SP100 Antikörper

Bindungsspezifität: AA 250-330

Verwendungszweck: Rabbit Anti-SP-100 Polyclonal Antibody

Spezifität: SP-100 Polyclonal Antibody detects endogenous levels of SP-100 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human SP-100 at AA range: 250-330

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SP100

Target: SP100 (SP100 Nuclear Antigen (SP100))

Andere Bezeichnung: SP-100

Hintergrund: SP100, Nuclear autoantigen Sp-100, Lysp100b, Nuclear dot-associated Sp100 protein, Speckled 100 kDaSP100 (SP100 nuclear antigen) encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for SP100, one of which encodes a high-mobility group protein.

Molekulargewicht: 100kD

Gen-ID: 6672

UniProt: P23497

Pathways: Retinoic Acid Receptor Signaling Pathway