SP100 Antikörper (AA 250-330)

Produktnummer ABIN7224440

Der Kaninchen Polyklonal Anti-SP100 Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, SP100 in Proben von Human zu detektieren.

Kurzübersicht für SP100 Antikörper (AA 250-330) (ABIN7224440)

Target: SP100 (SP100 Nuclear Antigen (SP100))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SP100 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SP100 Antikörper

Bindungsspezifität: AA 250-330

Verwendungszweck: SP-100 Polyclonal Antibody

Spezifität: SP-100 Polyclonal Antibody detects endogenous levels of SP-100 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human SP-100 at AA range: 250-330

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu SP100

Target: SP100 (SP100 Nuclear Antigen (SP100))

Andere Bezeichnung: SP-100

Hintergrund: Rabbit Anti-SP-100 Polyclonal Antibody,SP100, Nuclear autoantigen Sp-100, Lysp100b, Nuclear dot-associated Sp100 protein, Speckled 100 kDa,SP100 (SP100 nuclear antigen) encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for SP100, one of which encodes a high-mobility group protein.,Nuclear autoantigen Sp-100

Molekulargewicht: observerd band 100kDa

Gen-ID: 6672

UniProt: P23497

Pathways: Retinoic Acid Receptor Signaling Pathway