Sortilin 1 Antikörper (AA 260-340)

Produktnummer ABIN7231448

Der Kaninchen Polyklonal anti-Sortilin 1 Antikörper wird verwendet zum Nachweis von Sortilin 1 in Proben von Human, Ratte und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für Sortilin 1 Antikörper (AA 260-340) (ABIN7231448)

Target: Sortilin 1 (SORT1)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sortilin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Sortilin 1 Antikörper

Bindungsspezifität: AA 260-340

Verwendungszweck: Rabbit Anti-SORT Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of SORT protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SORT protein at AA range: 260-340

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Sortilin 1

Target: Sortilin 1 (SORT1)

Andere Bezeichnung: SORT

Hintergrund: Sortilin, 100 kDa NT receptor, Glycoprotein 95, Gp95, Neurotensin receptor 3, NT3, NTR3SORT1 encodes a member of the VPS10-related sortilin family of proteins. The encoded preproprotein is proteolytically processed by furin to generate the mature receptor. This receptor plays a role in the trafficking of different proteins to either the cell surface, or subcellular compartments such as lysosomes and endosomes. Expression levels of SORT1 may influence the risk of myocardial infarction in human patients. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 100kD

Gen-ID: 6272

UniProt: Q99523

Pathways: Neurotrophin Signalübertragung