Sortilin 1 Antikörper (AA 260-340)

Produktnummer ABIN7231448

Der Kaninchen Polyklonal Anti-Sortilin 1 Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Sortilin 1 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für Sortilin 1 Antikörper (AA 260-340) (ABIN7231448)

Target: Sortilin 1 (SORT1)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sortilin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Sortilin 1 Antikörper

Bindungsspezifität: AA 260-340

Verwendungszweck: SORT Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of SORT protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human SORT protein at AA range: 260-340

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Sortilin 1

Target: Sortilin 1 (SORT1)

Andere Bezeichnung: SORT

Hintergrund: Rabbit Anti-SORT Polyclonal Antibody,Sortilin, 100 kDa NT receptor, Glycoprotein 95, Gp95, Neurotensin receptor 3, NT3, NTR3,SORT1 encodes a member of the VPS10-related sortilin family of proteins. The encoded preproprotein is proteolytically processed by furin to generate the mature receptor. This receptor plays a role in the trafficking of different proteins to either the cell surface, or subcellular compartments such as lysosomes and endosomes. Expression levels of SORT1 may influence the risk of myocardial infarction in human patients. Alternative splicing results in multiple transcript variants.,SORT

Molekulargewicht: observerd band 91kDa

Gen-ID: 6272

UniProt: Q99523

Pathways: Neurotrophin Signalübertragung