Der Kaninchen Polyklonal anti-SLC43A1 Antikörper (ABIN7217028) detektiert spezifisch SLC43A1 in WB, ELISA und IHC.
Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Haltbarkeit
12 months
Target
SLC43A1
(Solute Carrier Family 43, Member 1 (SLC43A1))
Andere Bezeichnung
SLC43A1
Hintergrund
SLC43A1, LAT3, PB39, POV1, Large neutral amino acids transporter small subunit 3, L-type amino acid transporter 3, Prostate cancer overexpressed gene 1 protein, Solute carrier family 43 member 1SLC43A1 belongs to the system L family of plasma membrane carrier proteins that transports large neutral amino acids (Babu et al. 2003 [PubMed 12930836]). supplied by OMIM, Mar 2008]SLC43A1 (Solute Carrier Family 43 Member 1) is a Protein Coding gene. Diseases associated with SLC43A1 include prostate cancer. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. Gene Ontology (GO) annotations related to this gene include neutral amino acid transmembrane transporter activity and L-amino acid transmembrane transporter activity. An important paralog of this gene is ENSG00000254979. Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.