SLC16A2/MCT8 Antikörper (AA 90-170)
Kurzübersicht für SLC16A2/MCT8 Antikörper (AA 90-170) (ABIN7224388)
Target
Alle SLC16A2/MCT8 (SLC16A2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 90-170
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Verwendungszweck
- MCT8 Polyclonal Antibody
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Spezifität
- MCT8 Polyclonal Antibody detects endogenous levels of MCT8 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human MCT8 at AA range: 90-170
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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Kommentare
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Primary Antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SLC16A2/MCT8 (SLC16A2) (Solute Carrier Family 16 Member 2 (SLC16A2))
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Andere Bezeichnung
- MCT8
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Hintergrund
- Rabbit Anti-MCT8 Polyclonal Antibody,SLC16A2, MCT8, XPCT, Monocarboxylate transporter 8, MCT 8, Monocarboxylate transporter 7, MCT 7, Solute carrier family 16 member 2, X-linked PEST-containing transporter,SLC16A2 (solute carrier family 16 member 2) encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). SLC16A2 is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in SLC16A2 are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. SLC16A2 is subject to X-chromosome inactivation. Mutations in SLC16A2 are the cause of Allan-Herndon-Dudley syndrome.,Monocarboxylate transporter 8
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Molekulargewicht
- observerd band 60kDa
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Gen-ID
- 6567
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UniProt
- P36021
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Pathways
- Hormone Transport
Target
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