SKIL Antikörper (AA 590-670)

Produktnummer ABIN7217066

Der Kaninchen Polyklonal Anti-SKIL Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, SKIL in Proben von Human und Maus zu detektieren.

Kurzübersicht für SKIL Antikörper (AA 590-670) (ABIN7217066)

Target: SKIL (SKI-Like Oncogene (SKIL))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SKIL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SKIL Antikörper

Bindungsspezifität: AA 590-670

Verwendungszweck: SnoN Polyclonal Antibody

Spezifität: SnoN Polyclonal Antibody detects endogenous levels of SnoN protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human SnoN at AA range: 590-670

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu SKIL

Target: SKIL (SKI-Like Oncogene (SKIL))

Andere Bezeichnung: SnoN

Hintergrund: Rabbit Anti-SnoN Polyclonal Antibody,SKIL, SNO, Ski-like protein, Ski-related oncogene, Ski-related protein,Ski-like protein encoded by SKIL is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.,Ski-like protein

Molekulargewicht: observerd band 77kDa

Gen-ID: 6498

UniProt: P12757

Pathways: Positive Regulation of Response to DNA Damage Stimulus