SIRPB1 Antikörper (AA 200-280)

Produktnummer ABIN7214046

Der Kaninchen Polyklonal anti-SIRPB1 Antikörper wird verwendet zum Nachweis von SIRPB1 in Proben von Human. Er wurde validiert für WB und ELISA.

Kurzübersicht für SIRPB1 Antikörper (AA 200-280) (ABIN7214046)

Target: SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIRPB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SIRPB1 Antikörper

Bindungsspezifität: AA 200-280

Verwendungszweck: Rabbit Anti-CD172b Polyclonal Antibody

Spezifität: CD172b Polyclonal Antibody detects endogenous levels of CD172b protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CD172b at AA range: 200-280

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SIRPB1

Target: SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

Andere Bezeichnung: CD172b

Hintergrund: SIRPB1, Signal-regulatory protein beta-1, SIRP-beta-1, CD172 antigen-like family member B, CD antigen CD172bSignal regulatory protein beta 1 encoded by SIRPB1 is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for SIRPB1.

Molekulargewicht: 48kD

Gen-ID: 10326

UniProt: O00241