SIGLEC-5,SIGLEC-14 (Internal Region) Antikörper

Produktnummer ABIN7218076

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch SIGLEC-5,SIGLEC-14 in ELISA, IHC (p) und WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SIGLEC-5,SIGLEC-14 (Internal Region) Antikörper (ABIN7218076)

Target: SIGLEC-5,SIGLEC-14

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Produktdetails

Bindungsspezifität: Internal Region

Verwendungszweck: Siglec-5/14 Polyclonal Antibody

Spezifität: Siglec-5/14 Polyclonal Antibody detects endogenous levels of Siglec-5/14 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Siglec-5/14

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Antigendetails

Target: SIGLEC-5,SIGLEC-14

Andere Bezeichnung: Siglec-5/14

Hintergrund: Rabbit Anti-Siglec-5/14 Polyclonal Antibody,SIGLEC5, CD33L2, OBBP2, Sialic acid-binding Ig-like lectin 5, Siglec-5, CD33 antigen-like 2, Obesity-binding protein 2, OB-BP2, OB-binding protein 2, CD170, SIGLEC14, Sialic acid-binding Ig-like lectin 14, Siglec-14,SIGLEC5 encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The sialic acid binding Ig like lectin 5 is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.,Sialic acid-binding Ig-like lectin 5

Molekulargewicht: observerd band 60kDa

Gen-ID: 8778

UniProt: O15389