SGOL2 Antikörper (AA 650-730)

Produktnummer ABIN7219846

Der Kaninchen Polyklonal Anti-SGOL2 Antikörper wurde für ELISA und IHC (p) validiert. Er ist geeignet, SGOL2 in Proben von Human zu detektieren.

Kurzübersicht für SGOL2 Antikörper (AA 650-730) (ABIN7219846)

Target: SGOL2 (Shugoshin-Like 2 (SGOL2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SGOL2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SGOL2 Antikörper

Bindungsspezifität: AA 650-730

Verwendungszweck: Sgo2 Polyclonal Antibody

Spezifität: Sgo2 Polyclonal Antibody detects endogenous levels of Sgo2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Sgo2 at AA range: 650-730

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu SGOL2

Target: SGOL2 (Shugoshin-Like 2 (SGOL2))

Andere Bezeichnung: Sgo2

Hintergrund: Rabbit Anti-Sgo2 Polyclonal Antibody,SGOL2, Shugoshin-like 2, Shugoshin-2, Sgo2, Tripin,Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments.,Shugoshin-like 2

Gen-ID: 151246

UniProt: Q562F6