Septin 5 Antikörper (AA 180-260)

Produktnummer ABIN7223244

Der Kaninchen Polyklonal Anti-Septin 5 Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Septin 5 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für Septin 5 Antikörper (AA 180-260) (ABIN7223244)

Target: Septin 5 (SEPT5)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Septin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Septin 5 Antikörper

Bindungsspezifität: AA 180-260

Verwendungszweck: Septin 5 Polyclonal Antibody

Spezifität: Septin 5 Polyclonal Antibody detects endogenous levels of Septin 5 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Septin 5 at AA range: 180-260

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Septin 5

Target: Septin 5 (SEPT5)

Andere Bezeichnung: Septin 5

Hintergrund: Rabbit Anti-Septin 5 Polyclonal Antibody,SEPT5, PNUTL1, Septin-5, Cell division control-related protein 1, CDCrel-1, Peanut-like protein 1,SEPT5 (septin 5) is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. SEPT5 is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and SEPT5 has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.,Septin-5

Molekulargewicht: observerd band 42kDa

Gen-ID: 5413

UniProt: Q99719

Pathways: Synaptic Vesicle Exocytosis